Characteristic	N	Overall, N = 3911	no, N = 3141	yes, N = 771	
Age	391	66 (57;74) [24,90]	64 (56;72) [24,87]	72 (66;79) [31,90]	
Male	391	275 (70%)	227 (72%)	48 (62%)	
Living alone	385	107 (28%)	70 (23%)	37 (49%)	
Pre-stroke PASE score	391	167 (122;225) [85,574]	174 (135;231) [85,574]	123 (103;184) [85,407]	
Daily or occasinally smoking	391	119 (30%)	90 (29%)	29 (38%)	
More alcohol than recommendation	381	34 (8.9%)	25 (8.2%)	9 (12%)	
Known AFIB	386	57 (15%)	45 (15%)	12 (16%)	
Known hypertension	387	184 (48%)	139 (45%)	45 (59%)	
Known diabetes	391	37 (9.5%)	29 (9.2%)	8 (10%)	
Known PAD	391	12 (3.1%)	8 (2.5%)	4 (5.2%)	
Previous MI	391	33 (8.4%)	24 (7.6%)	9 (12%)	
Previous TIA	386	10 (2.6%)	8 (2.6%)	2 (2.7%)	
Pre-stroke mRS  [-1]	391				
1		348 (89%)	284 (90%)	64 (83%)	
2		32 (8.2%)	25 (8.0%)	7 (9.1%)	
3		10 (2.6%)	5 (1.6%)	5 (6.5%)	
4		1 (0.3%)	0 (0%)	1 (1.3%)	
Acute NIHSS score	388	3.0 (2.0;5.0) [0.0,32.0]	3.0 (2.0;5.0) [0.0,32.0]	3.0 (2.0;7.0) [0.0,22.0]	
Any reperfusion therapy	391	151 (39%)	123 (39%)	28 (36%)	
Active trial treatment	391	190 (49%)	147 (47%)	43 (56%)	
Six month PASE score	391	159 (101;225) [0,486]	180 (135;240) [86,486]	57 (34;68) [0,83]	
One month mRS [-1]	390	157 (40%)	136 (43%)	21 (27%)	
One month MFI (General fatigue)	378	10.0 (7.0;13.0) [4.0,20.0]	10.0 (7.0;13.0) [4.0,20.0]	12.0 (8.0;15.2) [4.0,20.0]	
One month MFI (Physical fatigue)	376	10.0 (7.0;14.0) [4.0,20.0]	9.0 (7.0;13.0) [4.0,20.0]	13.0 (7.8;17.0) [4.0,20.0]	
One month MFI (Reduced activity)	377	10.0 (7.0;13.0) [4.0,20.0]	9.0 (6.0;12.0) [4.0,20.0]	12.0 (9.0;16.0) [4.0,20.0]	
One month MFI (Reduced motivation)	378	7.00 (5.00;9.00) [4.00,20.00]	7.00 (5.00;9.00) [4.00,16.00]	8.00 (5.00;12.00) [4.00,20.00]	
One month MFI (Mental fatigue)	373	7.0 (4.0;11.0) [4.0,20.0]	7.0 (4.0;10.0) [4.0,20.0]	8.0 (5.0;12.0) [4.0,20.0]	
One month MDI	381	5.0 (3.0;9.0) [0.0,45.0]	5.0 (2.0;8.0) [0.0,37.0]	8.0 (4.0;15.0) [0.0,45.0]	
One month WHO5	385	76 (64;88) [0,100]	76 (64;88) [0,100]	70 (48;88) [0,100]	
PASE absolute decline	391	19 (-43;69) [-272,407]	1 (-55;38) [-272,349]	77 (45;127) [7,407]	
PASE relative decline	391	10 (-25;38) [-221,100]	1 (-34;22) [-221,68]	60 (41;75) [8,100]	
PASE score difference, relative F	391	0 (0%)	0 (0%)	0 (0%)	
PASE score difference, absolute F	391	0 (0%)	0 (0%)	0 (0%)	
PASE 0 quartiles	391	130 (33%)	83 (26%)	47 (61%)	
PASE 6 quartiles	391	82 (21%)	82 (26%)	0 (0%)	
PASE first quartile drop F	391	0 (0%)	0 (0%)	0 (0%)	
1Median (25%;75%) [Minimum,Maximum]; n (%)